Between space and medicine, you’d be hard-pressed to find a more regulated industry. This makes sense as these industries contain many of the same dangers. In space, vacuum tight seals are important for survival.
In medical devices, having precisely measured seals can also mean life and death, so regulations are just as stringent. The many different applications of heat seals in the industry (such as ports & plates) require the highest standard of equipment manufacturing to deliver consistent, validated results.